Here it is running in 2013 under VirtualBox.
Notice how DOS 6.22 even recognizes my AMD FX-8320 8 core processor.
The year 2013 doesn't seem to effect to operating system. Windows can go well past any Y2K fears.
Unlike Mac OS 9, I couldn't get Windows 3.11 to run 2560x1600 on a 30" screen. I don't know what to say about the 800x600 256 colors!